Wellbutrin 150 mg Tablet
Wellbutrin 150 mg is an oral tablet prescribed for the treatment of the major depressive disorder (MDD), seasonal affective disorder (SAD), and it is also used to help people in smoking cessation. It contains Bupropion (an antidepressant) that selectively inhibits the reuptake of norepinephrine and dopamine (NDRI). It also binds to the nicotinic acetylcholine receptors, thus activating these receptors without the use of cigarettes which helps people quit smoking. It is available in the form of both sustained release (SR) and extended release (XL) tablets. The sustained release tablet is usually to be taken twice a day- in the morning and afternoon, while the extended release tablet is usually to be taken once a day in the morning. However, the dose may vary depending on the prescription from your health-care provider. Do not overdose on this drug as it may cause seizures. In case you forget a dose, take it whenever you remember but do not take 2 consecutive doses.
How does Wellbutrin 150 mg work?
The active ingredient of Wellbutrin is Bupropion that belongs to the class of drugs known as antidepressants. It acts as both a norepinephrine-dopamine reuptake inhibitor (NDRI) and a non-competitive nicotinic receptor antagonist. The reuptake of dopamine is inhibited by Bupropion through dopamine and norepinephrine transporters which results in its antidepressant activity.
It is also a non-competitive antagonist of nicotinic acetylcholine receptors, that is, it binds to these receptors and helps in reducing the craving for cigarettes.
Uses of Wellbutrin 150 mg
It is used for the treatment of the following conditions-
- Major Depressive Disorder (MDD)- aka clinical depression. It is diagnosed by checking the symptoms given in the Diagnostic and Statistical Manual of Disorders (DSM).
- Seasonal Affective Disorder (SAD)- a specific type of depression that usually occurs in the fall and winter seasons. It is now called Major Depression with Seasonal Pattern.
- Smoking cessation- to break off the smoking habit.
The recommended dosage varies depending on the condition it is being used to treat but the usual starting dose is a tablet a day (taken in the morning). The dose may range from 150-450 mg per day. For smoking cessation, the usual dosage is one tablet per day for 3 consecutive days and twice a day for 7-10 weeks thereafter. The form and dose range is to be decided by your doctor. It can be consumed with food or on empty stomach. It’s to be swallowed intact without crushing, chewing, or breaking it.
What happens if I miss a dose?
For the sustained release (SR) form, take the missed dose as soon as you remember it. But do keep the consecutive doses 4 to 6 hours apart. A double dose is not to be taken.
For the extended release (XL) form, wait till it is time for your next scheduled dose. No extra tablet is to be taken to compensate for the missing dose.
What happens if I take an overdose?
In case of an overdose, immediately contact your doctor or a health-care emergency number or a poison control center because you may experience seizures, abnormal heartbeats, hallucination, and/ or unconsciousness.
Before you take this medicine
Wellbutrin 150 mg may not be suitable for you if you suffer from any medical condition. Before you take this medicine, let your doctor know:
- If you are allergic to Bupropion or any other medications.
- If you have an eating disorder.
- If you suffer from angle-closure glaucoma.
- If you suffer from a seizure disorder.
- If you have been diagnosed with bipolar disorder.
- If you’re pregnant or breastfeeding.
- If you’re taking, monoamine oxidase inhibitor or if you’ve stopped taking them in the last 2 weeks.
- If you consume large quantities of alcoholic beverages.
- If you have high blood pressure.
Discuss your medical history in detail with the doctor.
Side effects of Wellbutrin 150 mg
Bupropion can cause certain side effects. Some of the commonly reported ones are-
- Difficulty falling asleep or staying asleep
- Dry mouth
- Dizziness (avoid driving while under its influence)
- Stomach pain
- Uncontrollable shaking of a part of the body
- Loss of appetite
- Profusely sweating
- Ringing in the ears
- Changes in your sense of taste
- Sore throat
Some serious side-effects may include-
- Joint or muscle pain
- Irrational fears
- Heart palpitations or irregular heartbeats
- Swelling of the face or parts of the face, feet, or lower legs
- Chest pain
If any of the above-mentioned symptoms persist for long, stop the intake of medicine and contact your doctor immediately. This isn’t an exhaustive list of side-effects. If you experience any other unusual side effect of the medication, let your doctor know about it.
If you take any prescription or non-prescription medications, vitamins, or herbal supplements, let your doctor know about them. Certain medications can interact with Wellbutrin 150 mg and affect the way it works.
- Monoamine oxidase inhibitors like phenelzine, tranylcypromine, selegiline, and isocarboxazid.
- Other products containing Bupropion as an active ingredient.
- Other antipsychotics, antidepressants, tramadol, isoniazid, steroids, and hypoglycemic agents (like insulin) increase the risk of seizure.
- Nelfinavir or efavirenz
This isn’t a complete list of potential drug interactions. Discuss possible drug interactions with your doctor before starting this medicine.
Interaction with Alcohol
The risk of seizure increases with alcohol dependence. Tell your doctor in advance if you plan on stopping the consumption of alcohol suddenly.
You can store the tablets in the packaging it originally came in with the lid closed tight.
- Keep it out of reach of children.
- It should be stored under room temperature, away from direct sunlight, excessive heat and moisture.
- If the pack has expired, do not consume the pills.
- Safe disposal is necessary to keep your pets safe but do not flush the empty packaging in the toilet, rather gather information about take-back program by contacting the pharmacist or local recycling department.
Frequently Asked Questions (FAQs)
What is Wellbutrin 150 mg or Bupropion used for?
It is an antidepressant that helps with conditions like major depressive disorder (MDD), seasonal affective disorder (SAD), and help people quit smoking.
Does Wellbutrin or Bupropion XL cause weight-gain?
While all other antidepressants are related to weight-gain issues, Wellbutrin/ Bupropion XL rarely causes modest weight-gain, rather it’s related to modest weight-loss in the long-run.
When does Wellbutrin 150 mg/ Bupropion start working?
As you start taking the tablets, the symptoms will gradually decrease in about 2 weeks time. MDD and SAD symptoms related to sleep improve earlier than those related to willingness or mood to engage in activities. For smoking cessation, the time will be relatively shorter.
How effective is Wellbutrin 150 mg?
It is quite an effective antidepressant; comparable to other antidepressants and selective serotonin reuptake inhibitors. Both short and long-term treatments do well. However, some side-effects like nausea, constipation, dry mouth, insomnia, and dizziness are common.
|Working||Works by balancing the neurotransmitters in the brain|
|Kicks In||5-10 minutes usually and within a half-hour|
|Dosage||Up to 3 times a day|
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