|Active ingredient||Codeine Sulphate|
|Drug Class||Antitussives, narcotics, opioid analgesics|
|Kicks In||Within an hour|
|Treatment Period||Strictly decided by the doctor|
Codeine 60 mg
Codeine sulphate is a prescription medicine for pain. It is generally used to treat only mild symptoms pains but can also be prescribed in case of moderately severe pain. It may be used in combination with other drugs or alone, as per the requirements.
Being an opioid drug belonging to a class of drugs known as antitussives, codeine in a particular combination is also used to treat symptoms of flu, common cold, several allergies, hay fever, and other breathing-related issues (e.g., bronchitis, sinusitis). Alongside, it is also classified as a narcotic and opioid analgesic.
However, Codeine is preferably not prescribed to children younger than 12 years of age since it is not yet understood whether it is safe for them.
It is advised that Codeine be administered only to patients in need of medication for the treatment of mild to moderately severe symptoms of pain. This is because the drug is a narcotic pain reliever and tends to be addictive. Since Codeine is habit-forming, it should be taken only as the doctor suggests.
In a combination as Phenyleph-Chlorphen-Codeine, it is also prescribed to people suffering with cough and cold, flu, allergies, hay fever or some other problems related to breathing. Antihistamines in the combination help relieve watery eyes, itchiness, sneezing, and runny nose, while decongestants relieve stuffy nose and codeine helps reduce the urge to cough by working on a specific part of the brain.
While Codeine sulphate isn’t generally prescribed to children below 12 years of age, it is advised that the combination for treating cough not be administered to children younger than 18 as a result of being prone to serious side effects, especially some issues regarding breathing.
Dosage and Effects
Codeine sulphate is sold in the form of white, biconvex tablets and being a prescription medicine, it is advised that it only be taken in the dose and duration as your doctor advises. Codeine 60 mg is an important dose and alternatives include 30 mg and 15 mg tablets. Each of these tablets contains a designated amount of codeine sulphate and the following inactive ingredients: pregelatinized starch, microcrystalline cellulose, colloidal silicon dioxide and stearic acid.
Codeine sulphate is absorbed from the alimentary canal, mostly from the gastrointestinal tract, with maximum plasma concentration that occurs within an hour after administration. Therefore, its effectiveness can be observed in due time.
For the same, a precise dose should be decided upon by the physician, considering using non-opioid analgesics before Codeine and opioids on only an as needed basis. The usual adult dose varies among these and is repeated up to every four hours as per the requirement for pain. The maximum dose for 24 hours is not more than 360 mg in any case.
Being an opioid analgesic, it should be used with caution (as advised by the doctor) because of its addictiveness. On the other hand, some commonly occurring side effects of Codeine administration include drowsiness, dizziness, nausea, vomiting, stomach ache and constipation. These usually subside with regular, organized administration.
However, Codeine sulphate can also cause more severe effects, which include:
- Shallow breathing,
- Noisy breathing,
- Breathing that stops while you’re asleep,
- Weak pulse,
- Slow heart rate,
- Unusual thoughts or behavior,
- Unusual, extreme sadness or happiness,
- Seizure (convulsions),
- Loss of coordination,
- Fever and sweating,
- Problems with urination.
In the case of appearance of any of these symptoms in a quite serious manner is the sign for you to rush to your doctor. Get proper medical care to avoid any fatalities.
Codeine being an opioid drug, the users are prone to get addicted to it. To decrease the chances of this happening, it is advised that the prescription schedule be stringently followed.
It’s important that you discuss with your doctor your previous medication. While Codeine isn’t very much affected by other drugs, some of them might still affect how it functions in your body. Talk to the doctor about any side effects that might be bothering you. There’s a good chance that all the side effects aren’t a result of your dose.
In the elderly, codeine has also been known to cause confusion and over-sedation. To avoid most of that, dose selection for an elderly patient has to be cautious, starting at the lower end range, and changing only according to necessity.
A fraction of the population has a genetic variation that leads to the change of codeine to morphine in a more rapid manner than the average population, and that can affect their experience of the drug.
Codeine also gets secreted into human milk and, therefore, can affect the infant. In case of normal codeine metabolism, the amount of secreted is low and entirely dose-dependent. However, in those women that are ultra-rapid metabolizers of codeine, that may change, leading to higher levels of morphine in breast milk than normally expected. Alongside that, there can also be dangerously high serum morphine levels in such breastfed infants.
When children with evidence of ultra-rapid metabolization of codeine were administered with the drug following adenoidectomy or tonsillectomy, respiratory depression and death were observed as a result of a polymorphism.
Proper storage of Codeine 60 mg tablets is recommended to keep it effective for a long duration. Leaving the package uncared for also determines how the medicine affects you and might thus alter the results. For smart and safekeeping of the drugs, follow these steps:
- Store at a controlled room temperature, between 15° to 30°C, and away from moisture and light.
- Keep the tablets in a safe place, and preferably in their original packaging. Keep out of reach of children, since it can create serious health issues for them.
- The tablets usually come in blister packs, which aren’t child-resistant. Use child-resistant closure as per the requirement.
- All opioids are liable to abuse because of their addictive properties and are severely misused by both the general public and healthcare workers, so, these should be handled in accordance with that.
Frequently Asked Questions
What is Codeine sulphate used for?
Codeine tablets are used for the treatment of mild to moderately severe pain. However, they can also be used to treat flu, common cold, hay fever and related breathing issues.
How long does Codeine 60 mg take to work?
Codeine sulphate is absorbed from the alimentary canal, mostly from the gastrointestinal tract, with maximum plasma concentration that occurs within 60 minutes after administration. Therefore, its effectiveness can be observed in around an hour.
Is it okay to take Codeine tablets daily?
The usual adult dose for Codeine sulphate varies among 15 mg, 30 mg and 60 mg and is repeated up to every four hours as per the requirement for pain. The maximum dose for 24 hours is not more than 360 mg in any case.
Why does Codeine sulphate need careful consideration?
Being an opioid analgesic, the users of Codeine are prone to get addicted to the drug. Therefore, it is advised that only the prescribed dose as suggested by the physician should be administered. Any ill-regulated dose can prove to be fatal.